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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
12.42
Human Site:
Y865
Identified Species:
27.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
Y865
G
K
T
R
E
K
L
Y
D
F
V
K
T
E
R
Chimpanzee
Pan troglodytes
XP_526066
929
104074
L624
G
P
K
T
L
K
S
L
T
S
H
D
P
M
K
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
R884
E
R
L
G
T
R
E
R
L
Y
E
W
I
S
I
Dog
Lupus familis
XP_542327
1264
138869
R890
E
R
L
G
T
R
E
R
L
Y
E
W
I
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
Y868
G
K
M
R
E
K
L
Y
D
F
V
K
T
E
R
Rat
Rattus norvegicus
P97573
1190
133575
Y867
G
K
M
R
E
K
L
Y
D
F
V
K
T
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
H714
Q
A
V
L
Q
L
Q
H
F
K
G
R
D
Y
R
Chicken
Gallus gallus
XP_422567
1182
133482
Y864
G
K
Q
R
E
K
L
Y
D
F
V
K
I
E
R
Frog
Xenopus laevis
Q6P4S2
1019
115278
N714
T
S
Q
F
V
S
K
N
N
P
G
D
S
G
D
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
R868
E
R
M
G
T
R
E
R
L
Y
E
W
I
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
R870
E
S
L
Y
G
G
F
R
K
A
K
T
Y
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
13.3
0
0
N.A.
93.3
93.3
N.A.
6.6
86.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
20
20
N.A.
93.3
93.3
N.A.
26.6
86.6
13.3
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
37
0
0
19
10
0
10
% D
% Glu:
37
0
0
0
37
0
28
0
0
0
28
0
0
46
0
% E
% Phe:
0
0
0
10
0
0
10
0
10
37
0
0
0
0
0
% F
% Gly:
46
0
0
28
10
10
0
0
0
0
19
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
19
% I
% Lys:
0
37
10
0
0
46
10
0
10
10
10
37
0
0
10
% K
% Leu:
0
0
28
10
10
10
37
10
28
0
0
0
0
0
10
% L
% Met:
0
0
28
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% P
% Gln:
10
0
19
0
10
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
28
0
37
0
28
0
37
0
0
0
10
0
0
46
% R
% Ser:
0
19
0
0
0
10
10
0
0
10
0
0
10
28
0
% S
% Thr:
10
0
10
10
28
0
0
0
10
0
0
10
28
0
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
37
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
37
0
28
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _